Obituary writer Dan (Jude Law) is on his way to work when Alice (Natalie Portman) suddenly appears out of the London crowd and is just as suddenly knocked down by a car. He escorts her to hospital and from there develops a romance that will inspire his debut novel. Cut to Julia Roberts as Anna, a photographer who falls for Dan's charms when she's hired to snap his headshot. Initially reluctant to start an affair, she distracts herself with Larry (Clive Owen), a doctor inadvertently introduced to her through Dan. But as the years pass, insecurities bubble to the surface in both relationships, sparking a four-way tug of love.